Rosie O’Donnell’s friendship with Madonna made her realise she didn’t want to be hugely famous. The 62-year-old actress admitted being cast in 1992’s ‘A League of Their Own’ alongside the ‘Vogue’ hitmaker was “life-altering” for her because it made her reconsider what she wanted from her career as she got to see up close how “toxic” being a celebrity could be. She explained to David Duchovny on his ‘Fail Better’ podcast: “To be cast in a movie opposite the most famous woman in the world as the best friend — right, me and Madonna? That was like a life-altering casting session for me because it …