Scientists have uncovered a significant clue to understanding why some individuals are more susceptible to Alzheimer’s disease. Published in the journal Nature Communications, this new research reveals how a genetic variant called apolipoprotein E (APOE) interacts with a protein known as amyloid-beta. This interaction influences the likelihood of developing Alzheimer’s disease. Specifically, the study highlights that the APOE4 variant increases the harmful effects of amyloid-beta accumulation in the brain, providing a potential target for new therapies. Alzheimer’s disease is a debilitating ne…