The SMU Mustangs hit the road for the first time in a month this week, traveling to take on the No. 22-ranked Louisville Cardinals on Saturday. SMU, now 4-1, is coming off of a decisive victory over Florida State. They took down the Seminoles in their inaugural ACC matchup, 42-16. Meanwhile, Louisville is reeling from a 31-24 defeat against Notre Dame last weekend. After giving up 21 points in the first quarter, the Cardinals mounted a comeback effort that fell short in the fourth quarter. Despite their hot streak of late, the Mustangs enter the matchup against Louisville as a 6.5-point underd…