More than 5,000 genetic variants that enable certain cancers to thrive have been identified – along with a potential therapeutic target to treat or even prevent the tumours from developing. A study of all the possible genetic changes to the ‘tumour protection’ gene, BAP1, found a fifth of a them were pathogenic, significantly increasing the risk of developing cancers of the eye, lung lining, brain, skin, and kidney. The researchers from the Wellcome Sanger Institute, with collaborators at The Institute of Cancer Research in London and the University of Cambridge, also uncovered a link between …
