New research provides preliminary evidence that whole-body hyperthermia may have antidepressant effects that operate through the activation of an anti-inflammatory immune signaling pathway. The findings have been published in the journal Brain, Behavior, and Immunity. Depression is a leading cause of disability worldwide and is expected to become the largest contributor to global disease burden by 2030. Despite the availability of various antidepressant treatments, their effectiveness remains limited for many individuals. This has driven researchers to explore alternative treatments and better…